Postdoctoral Researcher

The University Health Network, where "above all else the needs of patients come first", encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of "Transforming lives and communities through excellence in care, discovery and learning", the University Health Network (UHN), Canada's largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

Union: Non-Union
Site: Krembil Research Institute
Department: Medicinal Chemistry
Reports to: Principal Investigator
Work Model: Hybrid
Grade: V0:90
Hours: 37.5 hours per week
Salary: $53,303 - $69,293 Annually (To commensurate with experience and consistent with UHN compensation policy)
Shifts: Monday to Friday
Status: Temporary Full-Time (1 year, with option to extend)
Closing Date: December 31, 2024

Position Summary
The laboratory of Dr. Donald Weaver, Krembil Research Institute, (University Health Network) and Department of Chemistry (University of Toronto) invites applications for one Postdoctoral Researcher Position in Computational/Theoretical Chemistry. Work will involve applications of molecular modelling methods (molecular dynamics/molecular mechanics/quantum mechanics calculations) to understanding neurochemical processes, developing in silico disease models and participating in a multi-disciplinary group focused on drug design for neurodegenerative disease.

Applicants should hold a PhD in Computational/Theoretical Chemistry (must be obtained within the previous 5 years) and have a strong background in the development and use of molecular modelling and electronic structure theory. The successful candidate will work in the Krembil Research Institute, which is part of the Toronto Western Hospital. We expect strong commitment, good communication skills and ability to work in a multidisciplinary environment with highly qualified professionals from international backgrounds.

Major topics of research include:

• Molecular dynamics simulations
• Molecular mechanics optimizations/protein modelling
• DFT and molecular orbital ab initio calculations
• Applications to neurochemistry, small molecule structure and hydration/solvation

Duties

• Performing molecular modelling simulations
• Performing molecular dynamics simulations
• Performing molecular mechanics calculations
• Performing molecular quantum mechanics calculations
• Computational protein modelling
• Computer-aided drug design

• PhD in computational/theoretical chemistry must be obtained within the previous five (5) years
• Strong background in molecular modelling
• Willingness to work in multidisciplinary group focussed on drug discovery

Why join UHN?
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.